Milk is the rich source of protein which plays very important role of structure, function and regulation of the body’s tissues and organs.
The beta casein protein in the milk is the folded chain of 209 amino acid. There are at least eight variant of beta casein these are A, B, C, D, E and F, reflecting in the order in which they were identified.
Subsequently, the A beta casein sub divided into three types, now known as A1, A2 and A3. Out of which A1 and A2 are most known types.
The only difference between A1 and A2 beta caseins is the amino acid at position 67. In case of A1 beta casein the amino acid at position 67 is histidine, whereas with A2 beta casein is the amino acid proline.
This tiny difference in the protein structure can have major effect when the protein is digested. The reason is that proline binds very closely to the amino acid next to it in position 66, whereas histidine linkage easily broken by digestive enzymes. The outcome of all this is that digestion of A1 beta casein can produce a peptide of a string of seven amino acids called beta-casomorphin-7 (BCM 7). And this BCM7 have opioid (narcotic) properties. BCM7 is responsible for many diseases such as Autism, type-1 diabetes in the children. Cardiac disease, schizophrenia, SIDS (Sudden Infant Death Syndrome) in common human being.
An agriculture professor at New Zealand’s Lincon’s University, Keith Woodford has authenticated the same conflict by tagging A1 milk producing Cow as “Devil in the Milk”, because of the presence of BCM7 (betacasomorphine) in its milk.